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CACNB2 antibody (AA 189-205)

CACNB2 Reactivity: Human, Rat, Mouse WB, IHC, IF, ICC Host: Mouse Monoclonal S8b-1 unconjugated
Catalog No. ABIN1721488
  • Target See all CACNB2 Antibodies
    CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))
    Binding Specificity
    • 11
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 189-205
    Reactivity
    • 64
    • 43
    • 32
    • 14
    • 13
    • 12
    • 12
    • 9
    • 9
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 60
    • 18
    • 1
    Mouse
    Clonality
    • 62
    • 17
    Monoclonal
    Conjugate
    • 44
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CACNB2 antibody is un-conjugated
    Application
    • 65
    • 33
    • 20
    • 16
    • 13
    • 12
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Reacts with human, mouse and rat Cavβ2 Ca+2 Channel.It does not cross-react with Cav β1, Cav β3, or Cav β4.
    Purification
    Purified
    Immunogen
    Synthetic peptide corresponding to aa 189-205 of rat Cavbeta2 (RSPKPSANSVTSPHSKE) (accession no. NP_446303).
    Clone
    S8b-1
    Isotype
    IgG1
    Top Product
    Discover our top product CACNB2 Primary Antibody
  • Application Notes
    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    WB(1 - 10 μg/mL) ICC (0.1 - 1 μg/mL) IF(1 - 10 μg/mL)

    Positive control: Adult rat brain
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 50 % glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Dilute in PBS or medium that is identical to that used in the assay system.
    Storage
    -20 °C
    Storage Comment
    Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))
    Alternative Name
    Cavbeta2 Ca+2 Channel (CACNB2 Products)
    Synonyms
    CACNLB2 antibody, CAVB2 antibody, MYSB antibody, AW060387 antibody, CAB2 antibody, Cavbeta2 antibody, Cchb2 antibody, Cacnlb2 antibody, Cacnb2 antibody, CACNB2 antibody, CACNB2.2 antibody, cacnb2a antibody, im:7141271 antibody, si:dkey-32m20.2 antibody, calcium voltage-gated channel auxiliary subunit beta 2 antibody, calcium channel, voltage-dependent, beta 2 subunit antibody, calcium channel, voltage-dependent, beta 2b antibody, CACNB2 antibody, Cacnb2 antibody, cacnb2b antibody
    Background
    Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Cavβ subunits are involved in the transport of the pore-forming alpha1 subunit to the plasma membrane. They also shield an ER Retention signal on the alpha1 subunit, thereby guiding the poreforming subunit to the target membrane.

    Voltage-dependent L-type calcium channel subunit beta-2, CAB2 Calcium channel voltage-dependent subunit beta 2 Lambert-Eaton myasthenic syndrome antigen B, MYSB calcium channel, voltage-dependent, beta 2 subunit Gene name: CACNB2, CACNLB2, MYSB, CAVB2
    Gene ID
    783
    UniProt
    Q08289
    Pathways
    Skeletal Muscle Fiber Development
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