TGFBR3 antibody (AA 147-328)

Catalog No. ABIN1724752

Product Details anti-TGFBR3 Antibody

Target: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Binding Specificity: AA 147-328

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TGFBR3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogen: Purified recombinant fragment of human TGFBR3 (AA: 147-328 ) expressed in E. coli.

Clone: 1C5H11

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-TGFBR3 antibody (ABIN1724752)

Lambert, Huang, Mythreye, Blobe: "The type III transforming growth factor-? receptor inhibits proliferation, migration, and adhesion in human myeloma cells." in: Molecular biology of the cell, Vol. 22, Issue 9, pp. 1463-72, (2011) (PubMed).

Jiang, Liu, Lei, You, Zhou, Zhang: "[Defective expression of TGFBR3 gene and its molecular mechanisms in non-small cell lung cancer cell lines]." in: Zhongguo fei ai za zhi = Chinese journal of lung cancer, Vol. 13, Issue 5, pp. 451-7, (2010) (PubMed).

Target Details for TGFBR3

Target: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Alternative Name: TGFBR3 (TGFBR3 Products)

Synonyms: TGFBR3 antibody, DKFZp469I0915 antibody, BGCAN antibody, betaglycan antibody, 1110036H20Rik antibody, AU015626 antibody, AW215636 antibody, TBRIII antibody, transforming growth factor beta receptor 3 antibody, transforming growth factor, beta receptor III antibody, TGFBR3 antibody, tgfbr3 antibody, Tgfbr3 antibody

Background:

Description: This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. , ,

Aliases: BGCAN, betaglycan

Molecular Weight: 93.4 kDa

Gene ID: 7049

HGNC: 7049