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ABCG5 antibody (AA 306-367)

ABCG5 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 1B5E10 unconjugated
Catalog No. ABIN1724857
  • Target See all ABCG5 Antibodies
    ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
    Binding Specificity
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 306-367
    Reactivity
    • 22
    • 20
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 36
    • 2
    Mouse
    Clonality
    • 36
    • 2
    Monoclonal
    Conjugate
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCG5 antibody is un-conjugated
    Application
    • 28
    • 13
    • 13
    • 11
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. coli.
    Clone
    1B5E10
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Li, Yin, Wei, Yan, Aung, Wu, Wu, Lin, Liu, Pan: "ATP-binding cassette transporter G5 and G8 polymorphisms and several environmental factors with serum lipid levels." in: PLoS ONE, Vol. 7, Issue 5, pp. e37972, (2012) (PubMed).

    Johnson, Lee, Pickert, Urbatsch: "Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8." in: Biochemistry, Vol. 49, Issue 16, pp. 3403-11, (2010) (PubMed).

  • Target
    ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
    Alternative Name
    ABCG5 (ABCG5 Products)
    Synonyms
    DDBDRAFT_0205617 antibody, DDBDRAFT_0215344 antibody, DDB_0205617 antibody, DDB_0215344 antibody, STSL antibody, AW112016 antibody, cmp antibody, sterolin-1 antibody, trac antibody, ATP binding cassette subfamily G member 5 antibody, ATP-binding cassette, sub-family G (WHITE), member 5 antibody, ABC transporter G family protein antibody, ABCG5 antibody, abcg5 antibody, abcG5 antibody, Abcg5 antibody
    Background

    Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. , ,

    Aliases: STSL

    Molecular Weight
    72.5 kDa
    Gene ID
    64240
    HGNC
    64240
    Pathways
    Lipid Metabolism
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