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SOX10 antibody (AA 147-252)

SOX10 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 2E7E8 unconjugated
Catalog No. ABIN1724912
  • Target See all SOX10 Antibodies
    SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))
    Binding Specificity
    • 34
    • 16
    • 10
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-252
    Reactivity
    • 86
    • 54
    • 39
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 68
    • 37
    • 2
    Mouse
    Clonality
    • 55
    • 52
    Monoclonal
    Conjugate
    • 49
    • 9
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOX10 antibody is un-conjugated
    Application
    • 82
    • 37
    • 29
    • 28
    • 27
    • 18
    • 15
    • 14
    • 12
    • 10
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human SOX10 (AA: 147-252) expressed in E. coli.
    Clone
    2E7E8
    Isotype
    IgG1
    Top Product
    Discover our top product SOX10 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Shin, Vincent, Cuda, Xu, Kang, Kim, Taube: "Sox10 is expressed in primary melanocytic neoplasms of various histologies but not in fibrohistiocytic proliferations and histiocytoses." in: Journal of the American Academy of Dermatology, Vol. 67, Issue 4, pp. 717-26, (2012) (PubMed).

    Bannykh, Stolt, Kim, Perry, Wegner: "Oligodendroglial-specific transcriptional factor SOX10 is ubiquitously expressed in human gliomas." in: Journal of neuro-oncology, Vol. 76, Issue 2, pp. 115-27, (2006) (PubMed).

  • Target
    SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))
    Alternative Name
    SOX10 (SOX10 Products)
    Synonyms
    DOM antibody, PCWH antibody, WS2E antibody, WS4 antibody, WS4C antibody, SOX-10 antibody, SOX10 antibody, dom antibody, ws4 antibody, Dom antibody, Sox21 antibody, SOX9 antibody, cls/sox10 antibody, zgc:100757 antibody, SRY-box 10 antibody, SRY box 10 antibody, SRY-box 10 L homeolog antibody, SRY (sex determining region Y)-box 10 antibody, SOX10 antibody, Sox10 antibody, sox10.L antibody, sox10 antibody
    Background

    Description: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. ,

    Aliases: DOM, WS4, PCWH, WS2E, WS4C

    Molecular Weight
    49.9 kDa
    Gene ID
    6663
    HGNC
    6663
    Pathways
    Chromatin Binding
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