beta-2 Microglobulin antibody (beta-2-Microglobulin) (AA 21-100)

Details for Product anti-B2M Antibody No. ABIN1724934, Supplier: Log in to see
Antigen
  • Ly-m11
  • beta2-m
  • beta2m
  • bwm
  • wu:fa94c05
  • wu:fb10a09
  • b2m-W01
  • b2m-W03
  • b2m-Z01
  • b2m-Z02
  • b2m-Z03
  • B2M
  • b2m
  • B2MG
  • b-2-m
  • beta-2-microglobulin
  • beta-2 microglobulin
  • beta-2-microglobulin S homeolog
  • B2M
  • B2m
  • b2m
  • b2m.S
Alternatives
anti-Human beta-2 Microglobulin antibody for ELISA
Epitope
AA 21-100
32
23
14
12
10
10
7
7
5
4
3
3
2
2
2
2
2
1
1
1
1
Reactivity
Human
682
111
85
68
61
16
15
12
7
7
6
3
2
2
2
1
1
1
1
1
Host
Mouse
531
198
33
13
12
5
2
Clonality (Clone)
Monoclonal ()
Conjugate
This beta-2 Microglobulin antibody is un-conjugated
52
41
33
32
21
14
11
10
10
10
7
7
7
7
7
7
6
6
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
438
335
232
203
183
160
76
59
46
43
34
29
27
13
13
9
8
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Purified recombinant fragment of human B2M (AA 21-100) expressed in E. Coli.
Clone 4G5A1
Isotype IgG1
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others beta-2 Microglobulin products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name B2M (B2M Antibody Abstract)
Background This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. ,
Molecular Weight 13.7 kDa
Gene ID 567
HGNC 567
Pathways TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
ELISA image for anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody (ABIN1724934) anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody
Flow Cytometry (FACS) image for anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody (ABIN1724934) anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody (Image 2)
Immunocytochemistry (ICC) image for anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody (ABIN1724934) anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody (Image 3)
Western Blotting (WB) image for anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody (ABIN1724934) anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody (Image 4)
Western Blotting (WB) image for anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody (ABIN1724934) anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody (Image 5)
Immunohistochemistry (IHC) image for anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody (ABIN1724934) Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using B2M m...
Immunohistochemistry (IHC) image for anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody (ABIN1724934) Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using B2M...
Product cited in: Bernal, Ruiz-Cabello, Concha, Paschen, Garrido: "Implication of the ?2-microglobulin gene in the generation of tumor escape phenotypes." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 9, pp. 1359-71, 2012 (PubMed).

Hermansen, Hummelshøj, Lundsgaard, Hornum, Keller, Fleckner, Fox, Poulsen, Jacobsen: "Increased serum ?2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients." in: Lupus, Vol. 21, Issue 10, pp. 1098-104, 2012 (PubMed).

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