Anaphase Promoting Complex Subunit 11 (ANAPC11) (Internal Region) antibody

Details for Product No. ABIN1731759
Antigen
Epitope
Internal Region
6
3
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
67
26
23
Host
Rabbit
33
31
6
Clonality
Polyclonal
Conjugate
Un-conjugated
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
52
29
21
13
11
9
7
4
2
2
1
1
Options
Immunogen 18 amino acid peptide near the center of human APC11.
Isotype IgG
Specificity Reacts with human ANAPC11
Purification Antigen affinity purified
Antigen
Alternative Name ANAPC11 / APC11 (ANAPC11 Antibody Abstract)
Background Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
UniProt Q9NYG5
Application Notes

Working dilution: ELISA, IHC - P (5 μg/mL), WB (1 - 2 μg/mL)

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, Sodium azide 0.02 %
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Supplier Images
Image no. 1 for anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) (Internal Region) antibody (ABIN1731759) anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) (Internal Region) antibody (Image 1)
Image no. 2 for anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) (Internal Region) antibody (ABIN1731759) anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) (Internal Region) antibody (Image 2)