Neuroligin 1 antibody (NLGN1) (AA 718-843) (Atto 655)

Details for Product anti-NLGN1 Antibody No. ABIN1741311
Antigen
  • NLGN1
  • Nlgn1
  • GB18720
  • nlgn1
  • NL1
  • 6330415N05Rik
  • BB179718
  • mKIAA1070
  • neuroligin-1
  • neuroligin 1
  • NLGN1
  • LOC659779
  • LOC724358
  • nlgn1
  • Nlgn1
Epitope
AA 718-843
42
15
8
8
4
4
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
77
69
48
2
1
Host
Mouse
53
42
8
Clonality (Clone)
Monoclonal ()
Conjugate
This Neuroligin 1 antibody is conjugated to Atto 655
6
6
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
66
49
44
26
26
13
6
2
1
Options
Immunogen Fusion protein amino acids 718-843 (cytoplasmic C-terminus) of rat Neuroligin-1. Mouse: 99% identity (125/126 amino acids identical). Human: 99% identity (125/126 amino acids identical) >40% identity with Neuroligin-2 and -3.
Clone S97A-31
Isotype IgG1
Specificity Detects ~120 kDa. Does not cross-react with other Neuroligins.
Purification Protein G Purified
Plasmids, Primers & others Plasmids, Primers & others Neuroligin 1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Neuroligin 1 (NLGN1 Antibody Abstract)
Background Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord.
Gene ID 116647
UniProt Q62765
Pathways Synaptic Membrane, Synaptic Vesicle Exocytosis
Application Notes
  • WB (1:1000)
  • ICC/IF (1:100)
  • optimal dilutions for assays should be determined by the user.
Comment

2 μg/ml of SMC-463 was sufficient for detection of Neuroligin-1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Supplier Images
Image no. 1 for anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (Atto 655) (ABIN1741311) Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Neuroligin 1 Monoclo...
Image no. 2 for anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (Atto 655) (ABIN1741311) Western Blot analysis of Mouse Brain Membrane showing detection of ~120 kDa Neuroligi...
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