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APAF1 antibody (C-Term)

APAF1 Reactivity: Human, Mouse, Rat IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1804017
  • Target See all APAF1 Antibodies
    APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))
    Binding Specificity
    • 16
    • 15
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 84
    • 51
    • 50
    • 15
    • 1
    Human, Mouse, Rat
    Host
    • 71
    • 8
    • 7
    • 1
    Rabbit
    Clonality
    • 64
    • 23
    Polyclonal
    Conjugate
    • 43
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This APAF1 antibody is un-conjugated
    Application
    • 52
    • 27
    • 26
    • 26
    • 21
    • 15
    • 14
    • 13
    • 13
    • 11
    • 9
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Brand
    IHC-plus™
    Purification
    Immunoaffinity purified
    Immunogen
    A synthetic peptide derived from the C-terminus of human Apaf-1.

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product APAF1 Primary Antibody
  • Application Notes
    Approved: IHC, IHC-P (10 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    10 mM PBS,  pH 7.4, BSA, sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))
    Alternative Name
    APAF1 / APAF-1 (APAF1 Products)
    Synonyms
    APAF1 antibody, ARK antibody, Apaf-1 antibody, Apaf1 antibody, CG6829 antibody, D-Apaf-1 antibody, DARK antibody, Dapaf-1 antibody, Dapaf-1/HAC-1 antibody, Dark antibody, Dark/Apaf-I antibody, Dark/Dapaf-1/HAC1 antibody, Dark/Hac-1/dApaf-1 antibody, Dark/Hac-1/dApaf1 antibody, Dmel\\CG6829 antibody, Hac-1 antibody, Hac-1/Dark antibody, Hac1 antibody, T1 antibody, anon-53Fa antibody, apaf-1 antibody, apaf1 antibody, arc antibody, ark antibody, dAPAF-1 antibody, dApaf-1 antibody, dApaf-1/DARK/HAC-1 antibody, dApaf1 antibody, dArk antibody, dapaf antibody, dapaf-1 antibody, dapaf-1L antibody, dapaf-1S antibody, dark antibody, dark/dapaf-1/hac-1 antibody, dark/hac-1/dapaf-1 antibody, hac-1 antibody, hac1 antibody, l(2)SH0173 antibody, APAF-1 antibody, CED4 antibody, 6230400I06Rik antibody, Apaf1l antibody, fog antibody, mKIAA0413 antibody, zgc:136543 antibody, Death-associated APAF1-related killer antibody, apoptotic peptidase activating factor 1 L homeolog antibody, apoptotic peptidase activating factor 1 antibody, Dark antibody, apaf1.L antibody, apaf1 antibody, APAF1 antibody, Apaf1 antibody
    Background
    Name/Gene ID: APAF1
    Family: Apoptosis

    Synonyms: APAF1, APAF-1, CED4, KIAA0413
    Gene ID
    317
    UniProt
    O14727
    Pathways
    p53 Signaling, Apoptosis, Caspase Cascade in Apoptosis, Tube Formation, Positive Regulation of Endopeptidase Activity
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