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GABRG2 antibody (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2) (AA 10-100) Primary Antibody

GABRG2 Reactivity: Human, Mouse, Rat IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1841917
$454.67
Plus shipping costs $45.00
100 μL
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  • Target
    GABRG2
    Binding Specificity
    • 15
    • 13
    • 9
    • 7
    • 7
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-100
    Reactivity
    • 59
    • 45
    • 45
    • 21
    • 11
    • 10
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 59
    • 9
    • 1
    Rabbit
    Clonality
    • 68
    • 1
    Polyclonal
    Conjugate
    • 35
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GABRG2 antibody is un-conjugated
    Application
    • 56
    • 34
    • 19
    • 14
    • 14
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Specificity
    Specific for GABRG2.
    Purification
    Whole serum
    Immunogen
    A synthetic peptide from aa region 10-100 of mouse GABA A Receptor gamma 2 conjugated to an immunogenic carrier protein was used as the antigen.
  • Application Notes
    A dilution of 1 : 300 to 1 : 2000 is recommended.
    The optimal dilution should be determined by the end user.
    Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    GABRG2
    Abstract
    GABRG2 Antibody Abstract
    Synonyms
    cae2, eca2, gabrg1, gefsp3, si:ch211-145n14.1, CAE2, ECA2, GEFSP3, GABAA-R, Gabrg-2, gamma2, gamma-aminobutyric acid type A receptor gamma2 subunit, gamma-aminobutyric acid (GABA) A receptor, gamma 2, gamma-aminobutyric acid type A receptor gamma 2 subunit, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2, GABRG2, gabrg2, Gabrg2
    Background
    FUNCTION: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Defects in GABRG2 are the cause of childhood absence epilepsy type 2 (ECA2). Defects in GABRG2 are the cause of generalized epilepsy with febrile seizures plus type 3 (GEFS+3). Defects in GABRG2 are a cause of severe myoclonic epilepsy in infancy (SMEI). SUBCELLULAR LOCATION: Cell junction > synapse > postsynaptic cell membrane, Multi-pass membrane protein. Cell membrane, Multi-pass membrane protein.
    Synonyms: Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2, Gabrg2, GBRG2, GABA A Receptor gamma 2 Gamma-aminobutyric acid receptor subunit delta, GABRD
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