GABRG2 antibody (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2) (AA 10-100) Primary Antibody
- AA 10-100
- Human, Mouse, Rat
- This GABRG2 antibody is un-conjugated
- Immunohistochemistry (IHC), Western Blotting (WB)
- Specific for GABRG2.
- Whole serum
- A synthetic peptide from aa region 10-100 of mouse GABA A Receptor gamma 2 conjugated to an immunogenic carrier protein was used as the antigen.
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 41-140) antibody Primary Antibody
GABRG2 Reactivity: Human, Mouse, Rat, Rabbit ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugatedanti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (N-Term) antibody Primary Antibody
GABRG2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
- Application Notes
A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
- For Research Use only
- Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
- Handling Advice
- Avoid freeze and thaw cycles.
- 4 °C/-20 °C
- Storage Comment
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Expiry Date
- 12 months
- GABRG2 Antibody Abstract
- cae2, eca2, gabrg1, gefsp3, si:ch211-145n14.1, CAE2, ECA2, GEFSP3, GABAA-R, Gabrg-2, gamma2, gamma-aminobutyric acid type A receptor gamma2 subunit, gamma-aminobutyric acid (GABA) A receptor, gamma 2, gamma-aminobutyric acid type A receptor gamma 2 subunit, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2, GABRG2, gabrg2, Gabrg2
FUNCTION: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Defects in GABRG2 are the cause of childhood absence epilepsy type 2 (ECA2). Defects in GABRG2 are the cause of generalized epilepsy with febrile seizures plus type 3 (GEFS+3). Defects in GABRG2 are a cause of severe myoclonic epilepsy in infancy (SMEI). SUBCELLULAR LOCATION: Cell junction > synapse > postsynaptic cell membrane, Multi-pass membrane protein. Cell membrane, Multi-pass membrane protein.
Synonyms: Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2, Gabrg2, GBRG2, GABA A Receptor gamma 2 Gamma-aminobutyric acid receptor subunit delta, GABRD