Lysine (K)-Specific Methyltransferase 2B (KMT2B) (C-Term) antibody

Catalog No. ABIN184881

Product Details

Target: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Binding Specificity: C-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purpose: KMT2B/MLL4

Sequence: CNCGAKRCRR FLN

Cross-Reactivity: Dog, Human, Mouse, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: Peptide with sequence CNCGAKRCRRFLN, from the C Terminus of the protein sequence according to NP_055542.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Positive staining seen in paraffin embedded Human Testis and Human Brain Cortex. Recommended concentration: 5-10 μg/mL.

Western Blot: Using our routine western blotting protocol we would not expect to reliably detect proteins larger than 250 kDa (calculated MWt. of approx. 294KDa according to NP_055542.1).

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details

Target: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Alternative Name: KMT2B (KMT2B Products)

Background: KMT2B, MLL4, myeloid/lymphoid or mixed-lineage leukemia 4, HRX2, MLL2, KIAA0304, KIAA0304 gene product, DYT28, MLL1B, WBP7, WBP-7, CXXC10, Lysine methyltransferase 2B histone-lysine N-methyltransferase 2B[

Gene ID: 9757, 75410

NCBI Accession: NP_055542

Pathways: Warburg Effect