PDE4D antibody (AA 581-809)

Catalog No. ABIN1869726

Product Details anti-PDE4D Antibody

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Binding Specificity: AA 581-809

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purpose: Polyclonal Antibody to Phosphodiesterase 4D, cAMP Specific (PDE4D)

Specificity: The antibody is a rabbit polyclonal antibody raised against PDE4D. It has been selected for its ability to recognize PDE4D in immunohistochemical staining and western blotting.

Cross-Reactivity: Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Phosphodiesterase 4D, cAMP Specific (PDE4D) corresdonding to Leu581~Thr809 with N-terminal His and GST Tag

Isotype: IgG

Application Details

Application Notes:

Western blotting: 0.5-2 μg/mL Immunohistochemistry: 5-20 μg/mL Immunocytochemistry: 5-20 μg/mL Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for PDE4D

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Alternative Name: Phosphodiesterase 4D, cAMP Specific (PDE4D Products)

Synonyms: ACRDYS2 antibody, DPDE3 antibody, HSPDE4D antibody, PDE43 antibody, PDE4DN2 antibody, STRK1 antibody, CMYA2 antibody, MMGL antibody, 9630011N22Rik antibody, Dpde3 antibody, 4732458A06Rik antibody, 9430063L05Rik antibody, C87016 antibody, D130016K21Rik antibody, D3Bwg1078e antibody, Usmg4 antibody, mKIAA0454 antibody, si:dkey-190g11.2 antibody, phosphodiesterase 4D antibody, phosphodiesterase 4D interacting protein antibody, phosphodiesterase 4D, cAMP specific antibody, phosphodiesterase 4D, cAMP-specific antibody, phosphodiesterase 4D interacting protein (myomegalin) antibody, PDE4D antibody, PDE4DIP antibody, pde4d antibody, Pde4dip antibody, Pde4d antibody

Background: DPDE3, PDE43, Dunce(Drosophila)Homolog Phosphodiesterase E3, cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling