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RIPK1 antibody (AA 1-179)

RIPK1 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1870367
  • Target See all RIPK1 Antibodies
    RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
    Binding Specificity
    • 16
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-179
    Reactivity
    • 88
    • 39
    • 28
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Rat
    Host
    • 84
    • 11
    Rabbit
    Clonality
    • 75
    • 20
    Polyclonal
    Conjugate
    • 39
    • 9
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RIPK1 antibody is un-conjugated
    Application
    • 64
    • 33
    • 20
    • 15
    • 13
    • 13
    • 12
    • 12
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Purpose
    Polyclonal Antibody to Receptor Interacting Serine Threonine Kinase 1 (RIPK1)
    Specificity
    The antibody is a rabbit polyclonal antibody raised against RIPK1. It has been selected for its ability to recognize RIPK1 in immunohistochemical staining and western blotting.
    Cross-Reactivity
    Mouse
    Purification
    Antigen-specific affinity chromatography followed by Protein A affinity chromatography
    Immunogen
    Recombinant Receptor Interacting Serine Threonine Kinase 1 (RIPK1) corresdonding to Met1~Ala179 with N-terminal His Tag
    Isotype
    IgG
    Top Product
    Discover our top product RIPK1 Primary Antibody
  • Application Notes

    Western blotting: 0.5-2 μg/mL

    1:480-1900 Immunohistochemistry: 5-20 μg/mL

    1:48-190 Immunocytochemistry: 5-20 μg/mL

    1:48-190 Optimal working dilutions must be determined by end user.

    Comment

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.
    Preservative
    ProClin
    Precaution of Use
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
    Expiry Date
    24 months
  • Horiguchi, Yoshida, Hasegawa, Takigami, Ohsako, Kato, Kato: "Isolation and characterization of cluster of differentiation 9-positive ependymal cells as potential adult neural stem/progenitor cells in the third ventricle of adult rats." in: Cell and tissue research, Vol. 379, Issue 3, pp. 497-509, (2020) (PubMed).

  • Target
    RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
    Abstract
    RIPK1 Products
    Synonyms
    RIP antibody, RIP1 antibody, D330015H01Rik antibody, Rinp antibody, Rip1 antibody, rip1 antibody, ripk1 antibody, xRIP1beta antibody, xrip1 antibody, receptor interacting serine/threonine kinase 1 antibody, receptor (TNFRSF)-interacting serine-threonine kinase 1 antibody, receptor interacting serine/threonine kinase 1 L homeolog antibody, RIPK1 antibody, Ripk1 antibody, ripk1.L antibody
    Background
    RIP, Receptor-Interacting Protein, Cell death protein RIP, Serine/threonine-protein kinase RIP
    Pathways
    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway
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