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ABCC1 antibody (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1) Primary Antibody

ABCC1 Reactivity: Human FACS, IHC (fro), IHC (p), WB Host: Rat Monoclonal MRPr1 unconjugated
Catalog No. ABIN187338
$832.33
Plus shipping costs $45.00
1 mL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target
    ABCC1
    Reactivity
    • 80
    • 15
    • 15
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 47
    • 33
    • 2
    • 1
    Rat
    Clonality
    • 50
    • 33
    Monoclonal
    Conjugate
    • 41
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ABCC1 antibody is un-conjugated
    Application
    • 65
    • 52
    • 41
    • 23
    • 16
    • 13
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Specificity
    MRPr1 reacts with an epitope of Multidrug Resistance Protein 1 (MRP1, ABCC1), a 180-195 kDa transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines. MRPr1 does not cross-react with human MDR1 or MDR3 gene products. Species Reactivity: Human. Others not tested.
    Purification
    Supernatant
    Sterility
    0.22 μm filtered
    Immunogen
    Bacterial fusion protein of MRP containing a segment of 168 amino acids located in the amino-proximal half of the protein.Mouse myeloma (SP2/0) fused with immunized rat (outbred Wistar strain) lymph node cells.
    Clone
    MRPr1
    Isotype
    IgG2a
  • Application Notes
    Flow cytometry: After fixing cells in 10% (v/v) Lysing solution, use MRPr1 at a 1:20-1:50 dilution followed by FITC-conjugated anti-rat IgG secondary antibody. Immunocytochemistry: For acetone-fixed cell preparation use at a 1:20-1:50 dilution. Immunohistochemistry: For acetone-fixed frozen sections, use at a 1:20-1:50 dilution. For formalin-fixed, paraffin-embedded tissues, use at a 1:20 dilution. For paraffin-embedded sections, a 0.01 M citrate pretreatment for 10 min. at 100 °C may increase the performance of MRPr1. Western blot: Use at a 1:20-1:50 dilution, followed by anti-rat-HRP. The optimal dilution for a specific application should be determined by the researcher.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    1 mL (>200 tests) or 0.5 mL (>100 tests) monoclonal antibody at ~250 µg IgG/mL in serum-free tissue culture supernatant with protein stabilizer and 0.1% sodium azide. Filtered through a 0.22 µm filter. Culture medium: RPMI-1640, supplemented with Nutrid
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    ABCC1
    Alternative Name
    ABCC1 / MRP1 (ABCC1 Antibody Abstract)
    Synonyms
    ABC29, ABCC, GS-X, MRP, MRP1, Abcc1a, Abcc1b, Mdrap, Mrp1, Avcc1a, Mrp, ABCC13, ATP binding cassette subfamily C member 1, ATP-binding cassette, sub-family C (CFTR/MRP), member 1, multidrug resistance-associated protein 1, ABCC1, Abcc1, LOC100152428, LOC100346553
    Pathways
    SARS-CoV-2 Protein Interactome
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