ATP6AP2 antibody (AA 205-234)

Catalog No. ABIN1881092

Product Details anti-ATP6AP2 Antibody

Target: ATP6AP2 (ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2))

Binding Specificity: AA 205-234

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6AP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP6AP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human ATP6AP2.

Clone: RB41871

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ATP6AP2 antibody (ABIN1881092)

Takahashi, Yamamoto, Hirose, Hiraishi, Shoji, Shibasaki, Kato, Kaneko, Sasano, Satoh, Totsune: "Expression of (pro)renin receptor in human kidneys with end-stage kidney disease due to diabetic nephropathy." in: Peptides, Vol. 31, Issue 7, pp. 1405-8, (2010) (PubMed).

Cruciat, Ohkawara, Acebron, Karaulanov, Reinhard, Ingelfinger, Boutros, Niehrs: "Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling." in: Science (New York, N.Y.), Vol. 327, Issue 5964, pp. 459-63, (2010) (PubMed).

Nabi, Biswas, Nakagawa, Ichihara, Inagami, Suzuki: "Prorenin has high affinity multiple binding sites for (pro)renin receptor." in: Biochimica et biophysica acta, Vol. 1794, Issue 12, pp. 1838-47, (2009) (PubMed).

Alcazar, Cousins, Striker, Marin-Castano: "(Pro)renin receptor is expressed in human retinal pigment epithelium and participates in extracellular matrix remodeling." in: Experimental eye research, Vol. 89, Issue 5, pp. 638-47, (2009) (PubMed).

Takemitsu, Ichihara, Kaneshiro, Sakoda, Kurauchi-Mito, Narita, Kinouchi, Yamashita, Itoh: "Association of (pro)renin receptor mRNA expression with angiotensin-converting enzyme mRNA expression in human artery." in: American journal of nephrology, Vol. 30, Issue 4, pp. 361-70, (2009) (PubMed).

Target Details for ATP6AP2

Target: ATP6AP2 (ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2))

Alternative Name: ATP6AP2 (ATP6AP2 Products)

Synonyms: APT6M8-9 antibody, ATP6IP2 antibody, ATP6M8-9 antibody, ELDF10 antibody, M8-9 antibody, MRXE antibody, MSTP009 antibody, XMRE antibody, (P)RR antibody, 5730403E06Rik antibody, Atp6ip2 antibody, tj6 antibody, wss antibody, arcl antibody, j6b7 antibody, stv1 antibody, tj6m antibody, tj6s antibody, vph1 antibody, atp6a2 antibody, atp6n1d antibody, ATP6AP2 antibody, DKFZp459G0918 antibody, atp6ap2 antibody, wu:fj36c03 antibody, wu:fq15e04 antibody, zgc:73194 antibody, ATPase H+ transporting accessory protein 2 antibody, ATPase, H+ transporting, lysosomal accessory protein 2 antibody, ATPase H+ transporting V0 subunit d2 antibody, ATPase H+ transporting V0 subunit a2 antibody, ATPase, H+ transporting, lysosomal accessory protein 2 S homeolog antibody, ATP6AP2 antibody, Atp6ap2 antibody, ATP6V0D2 antibody, atp6v0a2 antibody, atp6ap2.S antibody, atp6ap2 antibody

Background: This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.

Molecular Weight: 39008

NCBI Accession: NP_005756

UniProt: O75787

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones