CPT2 antibody (AA 212-241)

Catalog No. ABIN1881226

Product Details anti-CPT2 Antibody

Target: CPT2 (Carnitine Palmitoyltransferase 2 (CPT2))

Binding Specificity: AA 212-241

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPT2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-241 amino acids from the Central region of human CPT2.

Clone: RB41839

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CPT2 antibody (ABIN1881226)

Lan, Fu, Liu, Huang, Chang, Liu, Peng, Chen: "High frequency of ETFDH c.250G>A mutation in Taiwanese patients with late-onset lipid storage myopathy." in: Clinical genetics, Vol. 78, Issue 6, pp. 565-9, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Ruaño, Thompson, Kane, Pullinger, Windemuth, Seip, Kocherla, Holford, Wu: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, (2010) (PubMed).

Hogan, Vladutiu: "Malignant hyperthermia-like syndrome and carnitine palmitoyltransferase II deficiency with heterozygous R503C mutation." in: Anesthesia and analgesia, Vol. 109, Issue 4, pp. 1070-2, (2009) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Target Details for CPT2

Target: CPT2 (Carnitine Palmitoyltransferase 2 (CPT2))

Alternative Name: CPT2 (CPT2 Products)

Background: The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders.

Molecular Weight: 73777

NCBI Accession: NP_000089

UniProt: P23786

Pathways: Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process