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GTPBP3 antibody (AA 293-320)

GTPBP3 Reactivity: Human WB Host: Rabbit Polyclonal RB40710 unconjugated
Catalog No. ABIN1881398
  • Target See all GTPBP3 Antibodies
    GTPBP3 (GTP Binding Protein 3 (Mitochondrial) (GTPBP3))
    Binding Specificity
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 293-320
    Reactivity
    • 13
    • 1
    • 1
    Human
    Host
    • 12
    • 1
    Rabbit
    Clonality
    • 13
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    This GTPBP3 antibody is un-conjugated
    Application
    • 12
    • 10
    • 4
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This GTPBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 amino acids from the Central region of human GTPBP3.
    Clone
    RB40710
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GTPBP3 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Reiling, van Vliet-Ostaptchouk, van t Riet, van Haeften, Arp, Hansen, Kremer, Groenewoud, van Hove, Romijn, Smit, Nijpels, Heine, Uitterlinden, Pedersen, Slagboom, Maassen, Hofker, t Hart, Dekker: "Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study." in: European journal of human genetics : EJHG, Vol. 17, Issue 8, pp. 1056-62, (2009) (PubMed).

    Villarroya, Prado, Esteve, Soriano, Aguado, Pérez-Martínez, Martínez-Ferrandis, Yim, Victor, Cebolla, Montaner, Knecht, Armengod: "Characterization of human GTPBP3, a GTP-binding protein involved in mitochondrial tRNA modification." in: Molecular and cellular biology, Vol. 28, Issue 24, pp. 7514-31, (2008) (PubMed).

    Bykhovskaya, Mengesha, Wang, Yang, Estivill, Shohat, Fischel-Ghodsian: "Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3." in: Molecular genetics and metabolism, Vol. 83, Issue 3, pp. 199-206, (2004) (PubMed).

    Li, Guan: "Identification and characterization of mouse GTPBP3 gene encoding a mitochondrial GTP-binding protein involved in tRNA modification." in: Biochemical and biophysical research communications, Vol. 312, Issue 3, pp. 747-54, (2003) (PubMed).

    Li, Guan: "A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation." in: Molecular and cellular biology, Vol. 22, Issue 21, pp. 7701-11, (2002) (PubMed).

  • Target
    GTPBP3 (GTP Binding Protein 3 (Mitochondrial) (GTPBP3))
    Alternative Name
    GTPBP3 (GTPBP3 Products)
    Synonyms
    GTPBP3 antibody, zgc:112394 antibody, 2410009F13Rik antibody, AI607903 antibody, GTPBG3 antibody, MSS1 antibody, MTGP1 antibody, THDF1 antibody, GTP binding protein 3, mitochondrial antibody, GTP binding protein 3 antibody, GTPBP3 antibody, Gtpbp3 antibody, gtpbp3 antibody
    Background
    This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.
    Molecular Weight
    52058
    NCBI Accession
    NP_001122327, NP_001182351, NP_116009, NP_598399
    UniProt
    Q969Y2
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