PPP2R2A antibody (N-Term)

Catalog No. ABIN1881683

Product Details anti-PPP2R2A Antibody

Target: PPP2R2A (Protein Phosphatase 2 Regulatory Subunit 2A (PPP2R2A))

Binding Specificity: AA 43-71, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R2A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Pr, M, Pig, Rb, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPP2R2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the N-terminal region of human PPP2R2A.

Clone: RB43624

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:25. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PPP2R2A antibody (ABIN1881683)

Li, Cai, Shouse, Piluso, Liu: "A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55." in: The EMBO journal, Vol. 26, Issue 2, pp. 402-11, (2007) (PubMed).

Nusbaum, Mikkelsen, Zody, Asakawa, Taudien, Garber, Kodira, Schueler, Shimizu, Whittaker, Chang, Cuomo, Dewar, FitzGerald, Yang, Allen, Anderson, Asakawa, Blechschmidt, Bloom, Borowsky, Butler, Cook et al.: "DNA sequence and analysis of human chromosome 8. ..." in: Nature, Vol. 439, Issue 7074, pp. 331-5, (2006) (PubMed).

Mayer, Hendrix, Cron, Matthies, Stone, Goris, Merlevede, Hofsteenge, Hemmings: "Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform." in: Biochemistry, Vol. 30, Issue 15, pp. 3589-97, (1991) (PubMed).

Target Details for PPP2R2A

Target: PPP2R2A (Protein Phosphatase 2 Regulatory Subunit 2A (PPP2R2A))

Alternative Name: PPP2R2A (PPP2R2A Products)

Synonyms: B55A antibody, B55ALPHA antibody, PR52A antibody, PR55A antibody, 2410004D02Rik antibody, mKIAA1541 antibody, PPP2R2A antibody, protein phosphatase 2 regulatory subunit Balpha antibody, protein phosphatase 2, regulatory subunit B, alpha antibody, PPP2R2A antibody, Ppp2r2a antibody

Background: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Molecular Weight: 51692

NCBI Accession: NP_001171062, NP_002708

UniProt: P63151

Pathways: Mitotic G1-G1/S Phases, Hepatitis C