STOML2 antibody (AA 161-189)

Catalog No. ABIN1881852

Product Details anti-STOML2 Antibody

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Binding Specificity: AA 161-189

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STOML2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STOML2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of human STOML2.

Clone: RB42787

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-STOML2 antibody (ABIN1881852)

Chang, Ma, Gong, Cui, Liu, Zhou, Zhou, Wang: "SLP-2 overexpression is associated with tumour distant metastasis and poor prognosis in pulmonary squamous cell carcinoma." in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, Vol. 15, Issue 2, pp. 104-10, (2010) (PubMed).

Da Cruz, De Marchi, Frieden, Parone, Martinou, Demaurex: "SLP-2 negatively modulates mitochondrial sodium-calcium exchange." in: Cell calcium, Vol. 47, Issue 1, pp. 11-8, (2010) (PubMed).

Grass, Preuss, Ahlgrimm, Fadle, Regitz, Pfoehler, Murawski, Pfreundschuh: "Association of a dominantly inherited hyperphosphorylated paraprotein target with sporadic and familial multiple myeloma and monoclonal gammopathy of undetermined significance: a case-control study." in: The lancet oncology, Vol. 10, Issue 10, pp. 950-6, (2009) (PubMed).

Kirchhof, Chau, Lemke, Vardhana, Darlington, Márquez, Taylor, Rizkalla, Blanca, Dustin, Madrenas: "Modulation of T cell activation by stomatin-like protein 2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 3, pp. 1927-36, (2008) (PubMed).

Target Details for STOML2

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Alternative Name: STOML2 (STOML2 Products)

Synonyms: zgc:63505 antibody, MGC116533 antibody, 0610038F01Rik antibody, MSLP2 antibody, SLP-2 antibody, stomatin (EPB72)-like 2 antibody, stomatin like 2 antibody, stomatin like 2 L homeolog antibody, stomatin (Epb7.2)-like 2 antibody, stoml2 antibody, STOML2 antibody, stoml2.L antibody, Stoml2 antibody

Background: STOML2 is similar in sequence to stomatin. It is a 356 amino acid protein with a calculated molecular mass of 38.5 kDa. STOML2 has 3 potential initiator sites, all sharing the same open reading frame. The STOML2 protein contains the cognate stomatin family consensus sequence, but it lacks the characteristic N-terminal hydrophobic domain and palmitoylation consensus sequence. STOML2 shares greatest sequence homology with stomatin and SLP1 in a region predicted to contain beta sheet and alpha helix structures. Northern blot analysis detected a 1.5 kb STOML2 transcript in all tissues examined, with highest levels in heart, liver, and pancreas. Western blot analysis detected STOML2 at apparent molecular masses of 45.5 kDa or 44.6 kDa in all human and mammalian cell lines and tissues examined, including red blood cells. Some cells also showed a faint band at about 34.3 kDa, which may represent translation from an alternate initiation site.

Molecular Weight: 38534

NCBI Accession: NP_038470

UniProt: Q9UJZ1

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection