SGK2 antibody (N-Term)

Catalog No. ABIN1882131

Product Details anti-SGK2 Antibody

Target: SGK2 (serum/glucocorticoid Regulated Kinase 2 (SGK2))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SGK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SGK2.

Clone: RB1192

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-SGK2 antibody (ABIN1882131)

Meng, Yamagiwa, Taffetani, Han, Patel: "IL-6 activates serum and glucocorticoid kinase via p38alpha mitogen-activated protein kinase pathway." in: American journal of physiology. Cell physiology, Vol. 289, Issue 4, pp. C971-81, (2005) (PubMed).

Friedrich, Feng, Cohen, Risler, Vandewalle, Bröer, Wang, Pearce, Lang: "The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC." in: Pflügers Archiv : European journal of physiology, Vol. 445, Issue 6, pp. 693-6, (2003) (PubMed).

Embark, Böhmer, Vallon, Luft, Lang: "Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms." in: Pflügers Archiv : European journal of physiology, Vol. 445, Issue 5, pp. 601-6, (2003) (PubMed).

Gamper, Fillon, Feng, Friedrich, Lang, Henke, Huber, Kobayashi, Cohen, Lang: "K+ channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK." in: Pflügers Archiv : European journal of physiology, Vol. 445, Issue 1, pp. 60-6, (2002) (PubMed).

Target Details for SGK2

Target: SGK2 (serum/glucocorticoid Regulated Kinase 2 (SGK2))

Alternative Name: SGK2 (SGK2 Products)

Synonyms: H-SGK2 antibody, dJ138B7.2 antibody, AI098171 antibody, AW146006 antibody, Sgkl antibody, SGK3 antibody, fm82b06 antibody, sgk2 antibody, wu:fm82b06 antibody, zgc:172111 antibody, zgc:198213 antibody, h-sgk2 antibody, SGK2 antibody, zgc:154065 antibody, SGK2, serine/threonine kinase 2 antibody, serum/glucocorticoid regulated kinase 2 antibody, serum/glucocorticoid regulated kinase 2a antibody, serum/glucocorticoid regulated kinase 2b antibody, SGK2 antibody, Sgk2 antibody, sgk2a antibody, sgk2 antibody, sgk2b antibody

Background: SGK2, a Ser/Thr protein kinase, is similar to serum- and glucocorticoid-induced protein kinase (SGK), but this gene product is not induced by serum or glucocorticoids. Expression is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK.

Molecular Weight: 47604

NCBI Accession: NP_001186193, NP_057360, NP_733794

UniProt: Q9HBY8