CCRK antibody

Catalog No. ABIN1882215

Product Details anti-CCRK Antibody

Target: CCRK (CDK20) (Cyclin-Dependent Kinase 20 (CDK20))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCRK antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged CCRK protein was used to produced this monoclonal antibody.

Clone: 885CT27-1-1

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CCRK antibody (ABIN1882215)

Wang, Kung: "Male germ cell-associated kinase is overexpressed in prostate cancer cells and causes mitotic defects via deregulation of APC/CCDH1." in: Oncogene, Vol. 31, Issue 24, pp. 2907-18, (2012) (PubMed).

Liu, Wu, Galaktionov: "p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells." in: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4507-14, (2004) (PubMed).

Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).

Target Details for CCRK

Target: CCRK (CDK20) (Cyclin-Dependent Kinase 20 (CDK20))

Alternative Name: CCRK (CDK20 Products)

Synonyms: CCRK antibody, CDCH antibody, P42 antibody, PNQALRE antibody, Ccrk antibody, 4932702G04Rik antibody, AU019450 antibody, AW558027 antibody, PNQLARE antibody, p42 antibody, cyclin dependent kinase 20 antibody, cyclin-dependent kinase 20 antibody, CDK20 antibody, Cdk20 antibody, cdk20 antibody

Background: Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.

Molecular Weight: 38695

NCBI Accession: NP_001034892, NP_001164110, NP_001164111, NP_036251, NP_848519

UniProt: Q8IZL9