GOLPH3 antibody

Catalog No. ABIN1882249

Product Details anti-GOLPH3 Antibody

Target: GOLPH3 (Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GOLPH3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged GOLPH3 protein was used to produced this monoclonal antibody.

Clone: 905CT9-1-1

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GOLPH3 antibody (ABIN1882249)

Zhang, Wang, Liu, Chen, Peng, Liang, Li, Xue, Li, Xia: "Overexpression of GOLPH3 is associated with poor prognosis and clinical progression in pancreatic ductal adenocarcinoma." in: BMC cancer, Vol. 14, pp. 571, (2014) (PubMed).

Nakashima-Kamimura, Asoh, Ishibashi, Mukai, Shidara, Oda, Munakata, Goto, Ohta: "MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction." in: Journal of cell science, Vol. 118, Issue Pt 22, pp. 5357-67, (2005) (PubMed).

Bell, Ward, Blackstock, Freeman, Choudhary, Lewis, Chotai, Fazel, Gushue, Paiement, Palcy, Chevet, Lafrenière-Roula, Solari, Thomas, Rowley, Bergeron: "Proteomics characterization of abundant Golgi membrane proteins." in: The Journal of biological chemistry, Vol. 276, Issue 7, pp. 5152-65, (2001) (PubMed).

Target Details for GOLPH3

Target: GOLPH3 (Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3))

Alternative Name: GOLPH3 (GOLPH3 Products)

Synonyms: wu:fj66a10 antibody, zgc:101573 antibody, zgc:110223 antibody, 4733401N08Rik antibody, 5730410D03Rik antibody, AW413496 antibody, GOPP1 antibody, GPP34 antibody, MIDAS antibody, Gmx33 antibody, golgi phosphoprotein 3 antibody, golph3 antibody, CpipJ_CPIJ009278 antibody, Golph3 antibody, GOLPH3 antibody

Background: Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains. Involved in modulation of mTOR signaling. Involved in the regulation of mitochondrial lipids, leading to increase of mitochondrial mass. Potential oncogene.

Molecular Weight: 33811

NCBI Accession: NP_071413

UniProt: Q9H4A6