LOX antibody (AA 234-260)
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- Target See all LOX Antibodies
- LOX (Lysyl Oxidase (LOX))
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Binding Specificity
- AA 234-260
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This LOX antibody is un-conjugated
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Application
- Western Blotting (WB)
- Predicted Reactivity
- M, Pig, Rat
- Purification
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Immunogen
- This LOX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.
- Clone
- 624CT23-7-3
- Isotype
- IgG2b
- Top Product
- Discover our top product LOX Primary Antibody
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- Application Notes
- WB: 1:100~500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 44, pp. 18892-7, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
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LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 44, pp. 18892-7, (2010) (PubMed).
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- Target
- LOX (Lysyl Oxidase (LOX))
- Alternative Name
- LOX (LOX Products)
- Synonyms
- LOX antibody, Xlox antibody, MGC146507 antibody, lox antibody, zgc:77447 antibody, AI893619 antibody, TSC-160 antibody, H-rev142 antibody, Rrg1 antibody, lysyl oxidase antibody, lysyl oxidase a antibody, lysyl oxidase L homeolog antibody, LOX antibody, lox antibody, loxa antibody, lox.L antibody, Lox antibody
- Background
- The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 46944
- NCBI Accession
- NP_002308
- UniProt
- P28300
- Pathways
- SARS-CoV-2 Protein Interactome
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