ARHGEF44 antibody, PRTPHN1 antibody, SCA4 antibody, 4931414L13Rik antibody, AI448583 antibody, mFLJ00068 antibody, RGD1310790 antibody, pleckstrin homology and RhoGEF domain containing G4 antibody, pleckstrin homology domain containing, family G (with RhoGef domain) member 4 antibody, PLEKHG4 antibody, Plekhg4 antibody
Background
The protein encoded by this gene contains multiple domains suggestive of a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus.Mutations in this gene are associated with spinocerebellar ataxia 16q22-linked.Several alternatively spliced transcript variants, differing only in the 5' UTR, or encoding a different isoform, have been found for this gene.[provided by RefSeq]