MEX3C antibody (C-Term)

Catalog No. ABIN1887027

Product Details anti-MEX3C Antibody

Target: MEX3C (Mex-3 Homolog C (C. Elegans) (MEX3C))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEX3C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide from near the carboxy terminus of human RKHD2.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for MEX3C

Target: MEX3C (Mex-3 Homolog C (C. Elegans) (MEX3C))

Alternative Name: Rkhd2 (MEX3C Products)

Synonyms: Rkhd2 antibody, RKHD2 antibody, rkhd2 antibody, bm-013 antibody, rnf194 antibody, MEX-3C antibody, RNF194 antibody, A130001D14Rik antibody, BC035207 antibody, BM-013 antibody, mex-3 RNA binding family member C antibody, mex3 RNA binding family member C antibody, Mex3c antibody, MEX3C antibody, mex3c antibody

Background: Rkhd2, also known as MEX3C is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module.MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway.These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms.It has been suggested that genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8.Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Synonyms: RING finger and KH domain-containing protein 2, RING finger protein 194, MEX3C, RNF194

NCBI Accession: NP_057710