TLR11 antibody (C-Term)

Catalog No. ABIN1887382

Product Details anti-TLR11 Antibody

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Binding Specificity: C-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Ion exchange chromatography purified

Immunogen: Peptide corresponding to 15 amino acids near the carboxy terminus of mouse TLR11.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for TLR11

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Alternative Name: TLR11 (Tlr11 Products)

Synonyms: RGD1564460 antibody, Gm287 antibody, toll-like receptor 11 antibody, Tlr11 antibody

Background: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors.TLR11 is one of three mouse TLRs that lack a human ortholog.It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.

NCBI Accession: NP_991388

Pathways: Activation of Innate immune Response