Transmembrane Protein 70 (TMM70) (Center) antibody

Catalog No. ABIN1887528

Product Details

Target: Transmembrane Protein 70 (TMM70)

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the center of human TMEM70.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details

Target: Transmembrane Protein 70 (TMM70)

Alternative Name: TMEM70 (TMM70 Products)

Synonyms: MC5DN2 antibody, 1110020A09Rik antibody, 2210416J16Rik antibody, RGD1566224 antibody, transmembrane protein 70 antibody, TMEM70 antibody, Tmem70 antibody

Background: TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes.Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer.Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms.It contains a conserved DUF1301 domain and two putative transmembrane regions.
Synonyms: Transmembrane protein 70

NCBI Accession: NP_060336