SLC39A14 antibody (Center)

Catalog No. ABIN1887629

Product Details anti-SLC39A14 Antibody

Target: SLC39A14 (Solute Carrier Family 39 (Zinc Transporter), Member 14 (SLC39A14))

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC39A14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): At least three isoforms of ZIP14 are known to exist, this antibody will detect both isoforms. ZIP14 antibody is predicted to not cross-react with other ZIP family members.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the center of human ZIP14.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for SLC39A14

Target: SLC39A14 (Solute Carrier Family 39 (Zinc Transporter), Member 14 (SLC39A14))

Alternative Name: ZIP14 (SLC39A14 Products)

Synonyms: LZT-Hs4 antibody, NET34 antibody, ZIP14 antibody, cig19 antibody, BC021530 antibody, G630015O18Rik antibody, Zip14 antibody, fad123 antibody, solute carrier family 39 member 14 antibody, solute carrier family 39 (zinc transporter), member 14 antibody, SLC39A14 antibody, Slc39a14 antibody

Background: The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters.Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation.The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA).ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1.ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6.In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.
Synonyms: Solute carrier family 39 member A14, Slc39A14, LZT-Hs4, NET34, CIG19

NCBI Accession: NP_001128625

Pathways: Transition Metal Ion Homeostasis