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KCNK18 antibody (Center)

KCNK18 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1887646
  • Target See all KCNK18 Antibodies
    KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    Center
    Reactivity
    Human, Mouse, Rat
    Host
    • 23
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNK18 antibody is un-conjugated
    Application
    • 16
    • 13
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid peptide from near the center of human TRESK.
    Top Product
    Discover our top product KCNK18 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Handling Advice
    Avoid freezing and thawing repeatly.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • Target
    KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))
    Alternative Name
    TRESK (KCNK18 Products)
    Synonyms
    K2p18.1 antibody, MGR13 antibody, TRESK antibody, TRESK-2 antibody, TRESK2 antibody, TRIK antibody, Gm781 antibody, Tresk antibody, Tresk-2 antibody, Trik antibody, potassium two pore domain channel subfamily K member 18 antibody, potassium channel, subfamily K, member 18 antibody, KCNK18 antibody, Kcnk18 antibody
    Background
    TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes.TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine.It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin.Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
    Synonyms: KCNK18, Potassium channel subfamily K member 18, TRIK, TRESK2
    NCBI Accession
    NP_862823
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