FREM2
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
FITC
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice
Avoid freezing and thawing repeatly.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
FREM2
(Fras1 Related Extracellular Matrix Protein 2 (FREM2))
6030440P17Rik antibody, 8430406N05Rik antibody, Gm409 antibody, b2b1562Clo antibody, my antibody, ne antibody, nv1 antibody, RGD1566012 antibody, FRAS1 related extracellular matrix protein 2 antibody, Fras1 related extracellular matrix protein 2 antibody, FREM2 antibody, Frem2 antibody
Background
FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome.FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia.The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis. Synonyms: FRAS1-related extracellular matrix protein 2