Shisa9
Reactivity: Mouse
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
Alexa Fluor 488
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice
Avoid freezing and thawing repeatly.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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Background
Shisa proteins are a recently-identified family of modulators of both FGF and Wnt signaling that block both maturation and transport to the cell surface of their respective receptors.SHISA9, also known as CKAMP44a, is a brain-specific type I transmembrane protein that associates with AMPA receptors in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses.It is thought to modulate short-term plasticity at specific excitatory synapses. Synonyms: Cystine-knot AMPAR modulating protein 44a, CKAMP44a, CKAMP44, FLJ10015