PCDH18 antibody (N-Term)

Catalog No. ABIN1888051

Product Details anti-PCDH18 Antibody

Target: PCDH18 (Protocadherin 18 (PCDH18))

Binding Specificity: N-Term

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDH18 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): At least three isoforms of PCDH18 are known to exist. This antibody is predicted to not cross-react with PCDH12.

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the amino terminus of human PCDH12.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for PCDH18

Target: PCDH18 (Protocadherin 18 (PCDH18))

Alternative Name: PCDH18 (PCDH18 Products)

Synonyms: PCDH68L antibody, 3110038E07Rik antibody, BB095589 antibody, protocadherin 18 antibody, PCDH18 antibody, Pcdh18 antibody

Background: Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules.Protocadherin 18 (PCDH18) was initially identified through screening of human and mouse ESTs using conserved cytoplasmic domain motifs.Tissue screening revealed PCDH18 broad expression in tissues such as brain, liver, heart, kidney, lung, and trachea.PCDH18 expression is also temporally and spatially regulated in the mouse embryonic brain and interacts with Disabled-1, an intracellular adapter protein involved in neuronal migration and cell positioning during mammalian brain development.PCDH18 was also found to be expressed in the developing zebrafish neural tube and central nervous system, lending support to the hypothesis that PCDH18 may play a role during brain development.
Synonyms: Protocadherin 18

NCBI Accession: NP_061908