Anoctamin 2 antibody (N-Term)

Catalog No. ABIN1888103

Product Details anti-Anoctamin 2 Antibody

Target: Anoctamin 2 (ANO2)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Anoctamin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide from near the amino terminus of human TMEM16B.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for Anoctamin 2

Target: Anoctamin 2 (ANO2)

Alternative Name: TMEM16B (ANO2 Products)

Synonyms: C12orf3 antibody, TMEM16B antibody, BC033409 antibody, Tmem16b antibody, tmem16b antibody, si:dkey-224k5.2 antibody, anoctamin 2 antibody, anoctamin-2 antibody, ANO2 antibody, Ano2 antibody, ano2 antibody, LOC100432927 antibody

Background: Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction.Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B.TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina.Like TMEM16A, TMEM16B is thought to form at least part of CaCC's but has different biophysical characteristics such as voltage dependence and unitary conductance.
Synonyms: Transmembrane protein 16B, Anoctamin 2, ANO2

NCBI Accession: NP_065106