Claudin 1 antibody

Catalog No. ABIN1944909

Product Details anti-Claudin 1 Antibody

Target: Claudin 1 (CLDN1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Storage: 4 °C,-20 °C

References for anti-Claudin 1 antibody (ABIN1944909)

Halford, Spencer, Greenwood, Winton, Hunt, Adamson: "Assignment of claudin-1 (CLDN1) to human chromosome 3q28-->q29 with somatic cell hybrids." in: Cytogenetics and cell genetics, Vol. 88, Issue 3-4, pp. 217, (2000) (PubMed).

Krämer, White, Kubbies, Swisshelm, Weber: "Genomic organization of claudin-1 and its assessment in hereditary and sporadic breast cancer." in: Human genetics, Vol. 107, Issue 3, pp. 249-56, (2000) (PubMed).

Swisshelm, Machl, Planitzer, Robertson, Kubbies, Hosier: "SEMP1, a senescence-associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily." in: Gene, Vol. 226, Issue 2, pp. 285-95, (1999) (PubMed).

Target Details for Claudin 1

Target: Claudin 1 (CLDN1)

Alternative Name: Claudin1 (CLDN1 Products)

Synonyms: CLD1 antibody, ILVASC antibody, SEMP1 antibody, AI596271 antibody, cldn19 antibody, claudin-1 antibody, cld1 antibody, ilvasc antibody, semp1 antibody, CLDN1 antibody, claudin 1 antibody, claudin 1 S homeolog antibody, CLDN1 antibody, Cldn1 antibody, cldn1 antibody, cldn1.S antibody

Background: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity). Acts as a co- receptor for HCV entry into hepatic cells.

Molecular Weight: 22744 Da

Gene ID: 9076

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C