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EIF3I antibody (AA 1-323) (HRP)

EIF3I Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN1992223
  • Target See all EIF3I Antibodies
    EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))
    Binding Specificity
    • 15
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-323
    Reactivity
    • 27
    • 19
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 40
    • 2
    Rabbit
    Clonality
    • 40
    • 2
    Polyclonal
    Conjugate
    • 12
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF3I antibody is conjugated to HRP
    Application
    • 29
    • 17
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Eukaryotic translation initiation factor 3 subunit I protein (1-323AA)
    Isotype
    IgG
    Top Product
    Discover our top product EIF3I Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze.
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))
    Alternative Name
    EIF3I (EIF3I Products)
    Synonyms
    EIF3S2 antibody, PRO2242 antibody, TRIP-1 antibody, TRIP1 antibody, eIF3-beta antibody, eIF3-p36 antibody, 36kDa antibody, D4Ertd632e antibody, Eif3s2 antibody, Trip1 antibody, eIF-3-beta antibody, eIF3 p36 antibody, eif3s2 antibody, hm:zehn0464 antibody, wu:fb62b08 antibody, zgc:56211 antibody, zgc:77823 antibody, CaO19.2967 antibody, eIF-3 39 kDa subunit homolog antibody, eIF3i antibody, eif3-beta antibody, eif3-p36 antibody, eif3i antibody, pro2242 antibody, trip-1 antibody, trip1 antibody, eukaryotic translation initiation factor 3 subunit I antibody, eukaryotic translation initiation factor 3, subunit I antibody, Eukaryotic Initiation Factor antibody, Eukaryotic translation initiation factor 3 subunit I antibody, translation initiation factor eIF3 subunit i antibody, eukaryotic translation initiation factor 3 subunit I L homeolog antibody, EIF3I antibody, Eif3i antibody, eif-3.I antibody, eIF3i antibody, eif3i antibody, TIF34 antibody, eif3i.L antibody
    Background

    Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).

    Aliases: eIF-3-beta antibody, eIF3 beta antibody, eIF3 p36 antibody, eIF3-beta antibody, eIF3-p36 antibody, eIF3i antibody, EIF3I_HUMAN antibody, EIF3S2 antibody, EIF3S2, formerly antibody, Eukaryotic translation initiation factor 3 subunit 2 antibody, Eukaryotic translation initiation factor 3 subunit 2 beta antibody, Eukaryotic translation initiation factor 3 subunit I antibody, eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD antibody, eukaryotic translation initiation factor 3, subunit 2 beta, 36 kDa antibody, eukaryotic translation initiation factor 3, subunit 2, formerly antibody, eukaryotic translation initiation factor 3, subunit I antibody, Predicted protein of HQ2242 antibody, PRO2242 antibody, TGF beta receptor interacting protein 1 antibody, TGF-beta receptor-interacting protein 1 antibody, TGFbeta receptor interacting protein 1 antibody, TGFbeta receptor-interacting protein 1 antibody, TRIP 1 antibody, TRIP-1 antibody, TRIP1 antibody

    UniProt
    Q13347
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA
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