KDM5A antibody (AA 437-603) (HRP)

Catalog No. ABIN1993036

Product Details anti-KDM5A Antibody (HRP)

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Binding Specificity: AA 437-603

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM5A antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Lysine-specific demethylase 5A protein (437-603AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KDM5A

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Alternative Name: KDM5A (KDM5A Products)

Synonyms: Jarid1a antibody, JARID1A antibody, RBBP-2 antibody, RBBP2 antibody, RBP2 antibody, AA409370 antibody, C76986 antibody, Rbbp2 antibody, lysine demethylase 5A antibody, lysine (K)-specific demethylase 5A antibody, Kdm5a antibody, KDM5A antibody

Background:

Background: Histone demethylase that specifically demethylates \'Lys-4\' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 \'Lys-9\', H3 \'Lys-27\', H3 \'Lys-36\', H3 \'Lys-79\' or H4 \'Lys-20\'. Demethylates trimethylated and dimethylated but not monomethylated H3 \'Lys-4\'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12.

Aliases: Histone demethylase JARID1A antibody, JARID1A antibody, Jumonji/ARID domain containing protein 1A antibody, Jumonji/ARID domain-containing protein 1A antibody, Kdm5a antibody, KDM5A_HUMAN antibody, Lysine-specific demethylase 5A antibody, RBBP-2 antibody, RBBP2 antibody, RBP2 antibody, Retinoblastoma binding protein 2 antibody, Retinoblastoma-binding protein 2 antibody

UniProt: P29375

Pathways: Chromatin Binding, Warburg Effect