Creatine Kinase MB antibody (AA 300-350)

Catalog No. ABIN2017593

Product Details anti-Creatine Kinase MB Antibody

Target: Creatine Kinase MB (CKM)

Binding Specificity: AA 300-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Creatine Kinase MB antibody is un-conjugated

Application: Please inquire

Specificity: Rabbit Anti-Creatine kinase MB Polyclonal Antibody detects endogenous levels of human, mouse and rat Creatine kinase M and Creatine kinase B.

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): This product has not been tested for other species yets.

Characteristics: Rabbit Anti-Creatine kinase MB Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 300~350 of human Creatine kinase M (Swiss Prot: P06732) and Creatine kinase B (Swiss Prot: P12277).

Purification: Immunoaffinity chromatography

Immunogen: KLH-coupled synthetic peptide within residues 300-350 of human Creatine kinase M and Creatine kinase B

Isotype: IgG

Application Details

Comment:

Positive Control: HEK293, SH-SY5Y, mouse brain and rat brain.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.

Concentration: 0.5 mg/mL

Buffer: Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles.

Storage: 4 °C/-20 °C

Storage Comment: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.

Target Details for Creatine Kinase MB

Target: Creatine Kinase MB (CKM)

Alternative Name: Creatine Kinase MB (CKM Products)

Synonyms: CKMM antibody, M-CK antibody, Ckmm antibody, MCK antibody, creatine kinase, M-type antibody, creatine kinase, muscle antibody, CKM antibody, Ckm antibody

Background: Creatine kinase (CK) is a major enzyme involved in energy metabolism in tissues with large fluctuations of energetic demand. CK catalyses the reversible transfer of a high energy phosphoryl group between ATP and phosphocreatine. Creatine kinase consists of B subunit (brain type) and M subunit (muscle type) and therefore three different cytosolic isoenzymes exist: CK-MM, CK-BB and CK-MB. The major muscle isoform, CK-MM, is a homodimer of the M subunit. In contrast to muscle, the major creatine kinase isoform in brain is BB creatine kinase. In a few tissues, especially myocardium, a heterodimeric isoform MB creatine kinase is present. Rabbit Anti-Creatine kinase MB Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 300~350 of human Creatine kinase M (Swiss Prot: P06732) and Creatine kinase B (Swiss Prot: P12277).
Synonyms: CKMB antibody

UniProt: P06732, P12277