DcR1 antibody

Catalog No. ABIN204177

Product Details anti-DcR1 Antibody

Target: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This DcR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Selected for its ability to detect mouse DcTRAIL R1 by immunohistochemistry. In Western Blots, this antibody shows less than 10 % cross-reactivity with rm4-1BB Ligand, rhBAFF R, rhDcTRAIL R3, rmFas, rmOPG, rhTRAIL R4 and does not cross-react with other proteins tested.

Purification: Protein G purified

Immunogen: NS0-derived rmDcTRAL R1.

Isotype: IgG2a

Application Details

Application Notes: Approved: ELISA, IHC, IHC-Fr, WB

Usage: Western Blot: This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect mouse DcTRAIL R1. Using a colorimetric detection system, the detection limit for rmDcTRAIL R1 is approximately 25 ng/lane under non-reducing conditions. Use of this antibody under reducing conditions is not recommended. Chemiluminescent detection will increase sensitivity by 5 to 50 fold. Immunohistochemistry: A biotin conjugate of this antibody was used at a concentration of 25 μg/mL with appropriate secondary reagents to detect DcTRAIL R1 in frozen mouse thymus tissue sections. Direct ELISA: This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect mouse DcTRAIL R1. The detection limit for rmDcTRAIL R1 is approximately 2 ng/well.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: deionized water

Concentration: Lot specific

Buffer: Lyophilized.

Target Details for DcR1

Target: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Alternative Name: TNFRSF10C / TRAIL-R3 / DCR1 (TNFRSF10C Products)

Synonyms: CD263 antibody, DCR1 antibody, DCR1-TNFR antibody, LIT antibody, TRAIL-R3 antibody, TRAILR3 antibody, TRID antibody, TNFRSF10C antibody, TNF receptor superfamily member 10c antibody, TNFRSF10C antibody

Background: Name/Gene ID: TNFRSF10C
Family: TNF Receptor

Synonyms: TNFRSF10C, CD263 antigen, CD263, Cytotoxic TRAIL receptor-3, Decoy receptor 1, DCR1, DCR1-TNFR, LIT, Lymphocyte inhibitor of TRAIL, TRAIL-R3, TRAILR3, TRAIL receptor 3, TRID

Gene ID: 8794

UniProt: O14798

Pathways: Apoptosis