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CD4 antibody

CD4 Reactivity: Human FACS, IP, Func, BR, Neut, Inhibition Host: Mouse Monoclonal MEM-115 unconjugated
Catalog No. ABIN206939
  • Target See all CD4 Antibodies
    CD4
    Reactivity
    • 354
    • 199
    • 113
    • 38
    • 24
    • 20
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    Human
    Host
    • 327
    • 146
    • 108
    • 4
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    • 1
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    Mouse
    Clonality
    • 444
    • 138
    • 3
    Monoclonal
    Conjugate
    • 194
    • 65
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    • 30
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    This CD4 antibody is un-conjugated
    Application
    • 469
    • 193
    • 99
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    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Blocking Reagent (BR), Neutralization (Neut), Blocking Antibody (Inhibition)
    Specificity
    Recognizes an epitope in the D1 domain of CD4 antigen, a 55 kD transmembrane glycoprotein expressed on a subset of T lymphocytes (helper T cells) and also on monocytes, tissue macrophages and granulocytes. It is negative in Western blotting even with non-reduced samples of cell lysates.
    Purification
    Protein A purified
    Immunogen
    Human thymocytes and T lymphocytes.

    Type of Immunogen: Cells
    Clone
    MEM-115
    Isotype
    IgG2a
    Top Product
    Discover our top product CD4 Primary Antibody
  • Application Notes
    Approved: Block, Flo, Func, Inhb, IP, Neut

    Usage: Immunoprecipitation: excellent. Functional Application: The antibody MEM-115 blocks binding of HIV gp120 to CD4 Molecule and it also strongly inhibits CD4-MHC Class II interactions. Flow Cytometry: Recommended dilution - 3 μg/mL. Application notes:. Altho

    Not recommended for: IHC-P
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Tris buffered saline (TBS), 15 mM sodium azide, approx,  pH 8.0.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    avoid freeze thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
  • Target
    CD4
    Alternative Name
    CD4 (CD4 Products)
    Synonyms
    cd4 antibody, L3T4 antibody, Ly-4 antibody, CD4mut antibody, W3/25 antibody, p55 antibody, CD4 molecule antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, T-cell surface glycoprotein CD4 antibody, CD4 antigen antibody, Cd4 molecule antibody, CD4 antibody, LOC100125525 antibody, cd4 antibody, Cd4 antibody
    Background
    Name/Gene ID: CD4

    Synonyms: CD4, CD4 antigen, CD4 receptor, CD4mut, CD4 antigen (p55), CD4 Molecule
    Gene ID
    920
    UniProt
    P01730
    Pathways
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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