PDE6A antibody (N-Term)

Catalog No. ABIN213543

Product Details anti-PDE6A Antibody

Target: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Hamster, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human PDE6A / PDE6 Alpha. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster (100%) Dog, Panda, Rabbit (94%) Bovine, Bat, Elephant (89%) Horse, Opossum (83%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 18 amino acid peptide from N-terminus of human PDE6A / PDE6 Alpha. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster (100%), Dog, Panda, Rabbit (94%), Bovine, Bat, Elephant (89%), Horse, Opossum (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (10 - 15 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PDE6A

Target: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Alternative Name: PDE6A (PDE6A Products)

Synonyms: si:bz1d10.3 antibody, si:rp71-1d10.3 antibody, CGPR-A antibody, PDEA antibody, RP43 antibody, Pdea antibody, nmf282 antibody, phosphodiesterase 6A, cGMP-specific, rod, alpha antibody, phosphodiesterase 6A antibody, pde6a antibody, PDE6A antibody, Pde6a antibody

Background: Name/Gene ID: PDE6A
Subfamily: PDE - photoreceptor
Family: Phosphodiesterase

Synonyms: PDE6A, Alpha-PDE, CGMP phosphodiesterase alpha, CGPR-A, PDE6alpha, PDE V-B1, PDEA, Phosphodiesterase 6a, RP43, GMP-PDE alpha

Gene ID: 5145

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction