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Metabotropic Glutamate Receptor 5 antibody (N-Term)

GRM5 Reactivity: Human, Rat, Mouse, Dog, Chicken, Monkey, Pig, Horse, Cow, Bat, Rabbit, Hamster IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN213594
  • Target See all Metabotropic Glutamate Receptor 5 (GRM5) Antibodies
    Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
    Binding Specificity
    • 41
    • 33
    • 16
    • 15
    • 13
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 112
    • 87
    • 83
    • 11
    • 8
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human, Rat, Mouse, Dog, Chicken, Monkey, Pig, Horse, Cow, Bat, Rabbit, Hamster
    Host
    • 92
    • 46
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 88
    • 55
    Polyclonal
    Conjugate
    • 45
    • 10
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Metabotropic Glutamate Receptor 5 antibody is un-conjugated
    Application
    • 121
    • 58
    • 41
    • 36
    • 31
    • 29
    • 19
    • 19
    • 13
    • 13
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Brand
    IHC-plus™
    Specificity
    Human GRM5 / MGLUR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Predicted Reactivity
    Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Bovine, Hamster, Horse, Rabbit, Pig, Turkey, Zebra finch, Chicken, Platypus, Lizard (100%) Xenopus (94%) Opossum, Pufferfish (88%) Zebrafish (82%).
    Purification
    Immunoaffinity purified
    Immunogen
    Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GRM5 / MGLUR5. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Bovine, Hamster, Horse, Rabbit, Pig, Turkey, Zebra finch, Chicken, Platypus, Lizard (100%), Xenopus (94%), Opossum, Pufferfish (88%), Zebrafish (82%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product GRM5 Primary Antibody
  • Application Notes
    Approved: IHC, IHC-P (5.6 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5.6 μg/mL.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS, less than 0.1 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
    Alternative Name
    GRM5 / MGLUR5 (GRM5 Products)
    Synonyms
    GPRC1E antibody, MGLUR5 antibody, mGlu5 antibody, mGluR5 antibody, mGlur5 antibody, 6430542K11Rik antibody, AI850523 antibody, Glu5R antibody, Gprc1e antibody, mGluR5b antibody, glutamate receptor, metabotropic 5 antibody, glutamate metabotropic receptor 5 antibody, GRM5 antibody, Grm5 antibody
    Background
    Name/Gene ID: GRM5
    Subfamily: Metabotropic glutamate
    Family: GPCR

    Synonyms: GRM5, GPRC1E, MGLUR5, Mglur5b, MGlu5
    Gene ID
    2915
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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