CCL17 antibody (AA 41-103)

Catalog No. ABIN2172678

Product Details anti-CCL17 Antibody

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Binding Specificity: AA 41-103

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL17 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CCL17

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CCL17 antibody (ABIN2172678)

Chen, Chiang: "Targeting TSLP With shRNA Alleviates Airway Inflammation and Decreases Epithelial CCL17 in a Murine Model of Asthma." in: Molecular therapy. Nucleic acids, Vol. 5, pp. e316, (2016) (PubMed).

Nakamura, Ito, Kobayashi, Herndon, Suzuki: "Orosomucoid 1 drives opportunistic infections through the polarization of monocytes to the M2b phenotype." in: Cytokine, Vol. 73, Issue 1, pp. 8-15, (2015) (PubMed).

Target Details for CCL17

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Alternative Name: CCL17 (CCL17 Products)

Synonyms: A-152E5.3 antibody, ABCD-2 antibody, SCYA17 antibody, TARC antibody, CCL17 antibody, Abcd-2 antibody, Scya17 antibody, Scya17l antibody, Tarc antibody, abcd2 antibody, C-C motif chemokine ligand 17 antibody, chemokine (C-C motif) ligand 17 antibody, ATP-binding cassette sub-family D member 2 antibody, CCL17 antibody, Ccl17 antibody, LOC100537809 antibody

Background:

Synonyms: Tarc, Abcd-2, Scya17, Scya17l

Background: Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. TARC displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. TARC binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

Gene ID: 20295