GRLF1 antibody (pTyr1087)

Catalog No. ABIN2174954

Product Details anti-GRLF1 Antibody

Target: GRLF1 (Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1))

Binding Specificity: pTyr1087

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRLF1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human GRLF1 around the phosphorylation site of Tyr1087

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GRLF1

Target: GRLF1 (Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1))

Alternative Name: GRLF1 (GRLF1 Products)

Synonyms: GRF-1 antibody, GRLF1 antibody, P190-A antibody, P190A antibody, p190ARhoGAP antibody, p190RhoGAP antibody, 6430596G11Rik antibody, AI841135 antibody, Arhgap35 antibody, mKIAA1722 antibody, p190A antibody, Grlf1 antibody, p190-A antibody, arhgap35 antibody, grf-1 antibody, grlf1 antibody, p190-a antibody, p190a antibody, p190arhogap antibody, p190rhogap antibody, Rho GTPase activating protein 35 antibody, Rho GTPase activating protein 35 L homeolog antibody, ARHGAP35 antibody, Arhgap35 antibody, arhgap35.L antibody

Background:

Synonyms: GRF-1, GRLF1, P190A, P190-A, p190RhoGAP, p190ARhoGAP, Rho GTPase-activating protein 35, Glucocorticoid receptor DNA-binding factor 1, Glucocorticoid receptor repression factor 1, Rho GAP p190A, ARHGAP35, GRF1, KIAA1722

Background: Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'-GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor.

Gene ID: 2909

UniProt: Q9NRY4

Pathways: Tube Formation