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INTU antibody (AA 320-350)

INTU Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2178384
  • Target See all INTU Antibodies
    INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))
    Binding Specificity
    • 4
    • 2
    • 2
    • 2
    • 1
    AA 320-350
    Reactivity
    • 24
    • 15
    • 14
    • 1
    Human, Mouse, Rat
    Host
    • 22
    • 2
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INTU antibody is un-conjugated
    Application
    • 20
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PDZD6
    Isotype
    IgG
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    Discover our top product INTU Primary Antibody
  • Application Notes
    WB 1:300-5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))
    Alternative Name
    PDZD6 (INTU Products)
    Synonyms
    9230116I04Rik antibody, 9430087H23Rik antibody, Pdzd6 antibody, Pdzk6 antibody, mKIAA1284 antibody, INT antibody, PDZD6 antibody, PDZK6 antibody, Xint antibody, in antibody, int antibody, pdzd6 antibody, inturned planar cell polarity protein antibody, inturned planar cell polarity protein S homeolog antibody, Intu antibody, INTU antibody, intu antibody, intu.S antibody
    Background

    Synonyms: Protein inturned, Inturned planar cell polarity effector homolog, PDZ domain-containing protein 6, INTU, KIAA1284, PDZD6, PDZK6, INTU_HUMAN.

    Background: Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).

    Gene ID
    27152
    UniProt
    Q9ULD6
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