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Vinexin antibody (AA 401-500)

Sorbs3 Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2180071
  • Target See all Vinexin (Sorbs3) Antibodies
    Vinexin (Sorbs3) (Sorbin and SH3 Domain Containing 3 (Sorbs3))
    Binding Specificity
    • 14
    • 7
    • 1
    AA 401-500
    Reactivity
    • 23
    • 2
    • 2
    Human
    Host
    • 23
    • 2
    Rabbit
    Clonality
    • 25
    Polyclonal
    Conjugate
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Vinexin antibody is un-conjugated
    Application
    • 21
    • 12
    • 12
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Vinexin
    Isotype
    IgG
    Top Product
    Discover our top product Sorbs3 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    Vinexin (Sorbs3) (Sorbin and SH3 Domain Containing 3 (Sorbs3))
    Alternative Name
    Vinexin (Sorbs3 Products)
    Synonyms
    zgc:113031 antibody, si:dkey-162f21.1 antibody, SCAM-1 antibody, SH3P3 antibody, Sh3d4 antibody, vinexin-g antibody, SCAM1 antibody, SH3D4 antibody, sorbin and SH3 domain containing 3 antibody, SORBS3 antibody, sorbs3 antibody, Sorbs3 antibody
    Background

    Synonyms: SCAM 1, SCAM1, SH3 containing adapter molecule 1, SH3 domain containing adapter molecule 1, SH3D4, Sorbin and SH3 domain containing 3, Sorbin and SH3 domain containing protein 3, Sorbs3, Vinexin alpha, Vinexin, Vinexin beta (SH3 containing adaptor molecule 1).

    Background: Vinexin is a 671 amino acid protein that is expressed as two isoforms, designated Vinexin alpha and Vinexin beta. Localized to cell junctions in both the cytoplasm and the cytoskeleton, Vinexin alpha functions to promote Actin stress fiber formation, playing an important role in modification of the Actin cytoskeleton. Like Vinexin alpha, Vinexin beta is localized to cell junctions in the cytoplasm, but is also found in the nucleus where it plays an important role in cell spreading and in activation of the JNK pathway in response to EGF stimulation. Although Vinexin alpha and Vinexin beta have different roles within the cell, both proteins contain three SH3 domains in their carboxy terminus and are expressed in a variety of tissues, including placenta, heart, liver, brain, pancreas and skeletal muscle. Together, Vinexin alpha and Vinexin beta are involved in cell-cell adhesion, signal transduction and cytoskeletal organization throughout the cell.

    Pathways
    MAPK Signaling
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