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LRG1 antibody

LRG1 Reactivity: Human WB, IA Host: Mouse Monoclonal 2F5-A2 unconjugated
Catalog No. ABIN2191876
  • Target See all LRG1 Antibodies
    LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))
    Reactivity
    • 71
    • 8
    • 8
    • 1
    • 1
    • 1
    Human
    Host
    • 59
    • 17
    • 1
    Mouse
    Clonality
    • 53
    • 24
    Monoclonal
    Conjugate
    • 51
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This LRG1 antibody is un-conjugated
    Application
    • 48
    • 25
    • 20
    • 14
    • 9
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunoassay (IA)
    Sterility
    0.2 μm filtered
    Clone
    2F5-A2
    Top Product
    Discover our top product LRG1 Primary Antibody
  • Application Notes
    and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    Restrictions
    For Research Use only
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Expiry Date
    12 months
  • Codina, Vanasse, Kelekar, Vezys, Jemmerson: "Cytochrome c-induced lymphocyte death from the outside in: inhibition by serum leucine-rich alpha-2-glycoprotein-1." in: Apoptosis : an international journal on programmed cell death, Vol. 15, Issue 2, pp. 139-52, (2010) (PubMed).

  • Target
    LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))
    Alternative Name
    Leucine-Rich alpha-2-Glycoprotein (LRG1 Products)
    Synonyms
    lrg antibody, HMFT1766 antibody, LRG antibody, 1300008B03Rik antibody, 2310031E04Rik antibody, Lrg antibody, Lrhg antibody, si:dkey-90m5.4 antibody, leucine rich alpha-2-glycoprotein 1 antibody, leucine-rich alpha-2-glycoprotein 1 L homeolog antibody, leucine-rich alpha-2-glycoprotein 1 antibody, perilipin-5 antibody, si:dkey-90m5.4 antibody, LRG1 antibody, lrg1.L antibody, Lrg1 antibody, PLIN5 antibody
    Background
    The monoclonal antibody recognizes leucine-rich alpha-2-glycoprotein (LRG), a member of the leucine- rich repeat family. LRG is a plasma protein of approximately 50 kDa. LRG consists of 312 amino acids. It has 1 galactosamine and 4 glucosamine oliogosacharides attached and has 2 intrachain disulfide bonds. Leucine comprises 66 of the 312 amino acids, and LRG contains at least eight 24-amino acid leucine-rich repeats. The consensus of these residues, termed leucine-rich repeats (LRR), has been identified as an LRR-containing domain. The primary function of LRRs is to provide versatile structural framework of the formation of protein-protein interactions. LRG is expressed during granulocyte differentiation. Although several family members of the leucine-rich repeat family have been shown to be involved in signal transduction, protein-protein interaction, or cell adhesion and development, a function for LRG remains elusive. LRG has been reported as a biomarker for certain diseases including microbial infections and cancer. LRG can be detected in human neutrophils and progenitor cells, but not in peripheral blood mononuclear cells. The monoclonal antibody 2F5.A2 can be used for immuno purification of human LRG. Aliases Leucine-rich alpha-2-glycoprotein, LRG Immunogen Human LRG, covalently coupled to hemocyanin using glutaraldehyde
    Pathways
    Brown Fat Cell Differentiation
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