Deleted In Azoospermia 4 (DAZ4) antibody

Details for Product No. ABIN2420941
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
52
18
18
4
3
3
2
2
2
2
Host
Rabbit
51
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA
34
23
18
13
8
1
1
Options
Immunogen Recombinant protein of human DAZ4
Isotype IgG
Purification Antigen affinity purification
Antigen
Alternative Name DAZ4 (DAZ4 Antibody Abstract)
Background This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms: pDP1680, pDP1681
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Image no. 1 for anti-Deleted In Azoospermia 4 (DAZ4) antibody (ABIN2420941) Immunohistochemistry of Human thyroid cancer using DAZ4 Polyclonal Antibody at diluti...
Image no. 2 for anti-Deleted In Azoospermia 4 (DAZ4) antibody (ABIN2420941) anti-Deleted In Azoospermia 4 (DAZ4) antibody (Image 2)