RETNLB antibody

Catalog No. ABIN2422115

Product Details anti-RETNLB Antibody

Target: RETNLB (Resistin Like beta (RETNLB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RETNLB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human RETNLB

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RETNLB

Target: RETNLB (Resistin Like beta (RETNLB))

Alternative Name: RETNLB (RETNLB Products)

Synonyms: FIZZ1 antibody, FIZZ2 antibody, HXCP2 antibody, RELM-beta antibody, RELMb antibody, RELMbeta antibody, XCP2 antibody, RETNLB antibody, 9030012B21Rik antibody, Fizz2 antibody, Relmb antibody, Xcp3 antibody, resistin like beta antibody, RETNLB antibody, Retnlb antibody

Background: Resistin-like betais aproteinthat in humans is encoded by theRETNLBgene. An infusion of either resistin or RELMB in rats rapidly induced severe hepatic but not peripheral insulin resistance. Increases in circulating resistin or RELMB levels markedly stimulated hepatic glucose production despite the presence of fixed physiologic insulin levels. This enhanced rate of glucose output was due to increased flux through glucose-6-phosphatase. The results supported the notion that a novel family of fat- and gut-derived circulating proteins modulates hepatic insulin action.

Pathways: Hormone Activity