PIM2 antibody

Catalog No. ABIN2422823

Product Details anti-PIM2 Antibody

Target: PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIM2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogen: Recombinant protein of human PIM2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PIM2

Target: PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))

Alternative Name: PIM2 (PIM2 Products)

Synonyms: cb1068 antibody, fj47b05 antibody, pim2 antibody, wu:fj47b05 antibody, DXCch3 antibody, Pim-2 antibody, Pim-2 proto-oncogene, serine/threonine kinase antibody, proviral integration site 2 antibody, pim2 antibody, PIM2 antibody, Pim2 antibody

Background: This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.