CBR1 antibody

Catalog No. ABIN2422895

Product Details anti-CBR1 Antibody

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human CBR1

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Alternative Name: CBR1 (CBR1 Products)

Synonyms: LOC100222525 antibody, MGC131152 antibody, CBR antibody, SDR21C1 antibody, hCBR1 antibody, 9-KPR antibody, AW261796 antibody, CR antibody, Cbr antibody, carbonyl reductase 1 antibody, carbonyl reductase [NADPH] 1 antibody, carbonyl reductase 1 S homeolog antibody, carbonyl reductase antibody, cbr1 antibody, CBR1 antibody, LOC100222525 antibody, cbr1.S antibody, Smp_033530.3 antibody, LOC610164 antibody, Cbr1 antibody

Background: Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.

Molecular Weight: Calculated MW: 30 kDa