PIP5K1B antibody

Catalog No. ABIN2422897

Product Details anti-PIP5K1B Antibody

Target: PIP5K1B (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIP5K1B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human PIP5K1B

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PIP5K1B

Target: PIP5K1B (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))

Alternative Name: PIP5K1B (PIP5K1B Products)

Synonyms: MSS4 antibody, STM7 antibody, AI844522 antibody, Pip5k1a antibody, Pipk5a antibody, Pipk5b antibody, MGC80809 antibody, pip5k1b antibody, zgc:101046 antibody, wu:fj29b05 antibody, wu:fj93b05 antibody, zgc:92316 antibody, phosphatidylinositol-4-phosphate 5-kinase type 1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type 1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta L homeolog antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta a antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta antibody, phosphatidylinositol 4-phosphate 5-kinase type-1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta b antibody, PIP5K1B antibody, Pip5k1b antibody, pip5k1b.L antibody, pip5k1ba antibody, pip5k1b antibody, LOC100472550 antibody, pip5k1bb antibody

Background: Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking, and cytoskeletal organization. The PIPK family is divided into type I, type II and type III . Each type of the PIPK family phosphorylate distinct substrates and they contain an activation loop, which determines their enzymatic specificity and subcellular targeting . The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I , , and , which are characterized by phosphorylating PI4P on the 5-hydroxyl . PIPK I (designated PIPK I in mouse) is expressed in brain tissue . PIPK I , designated PIPK I a in mouse, is also called STM7. PIPK I has two variants produced by alternative splicing which are expressed in lung, brain, and kidneys.

Pathways: PI3K-Akt Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization